500 Homers - It could be an absolute revolving door into the 500 home run club this season. Frank Thomas, now with Toronto, has 487. Jim Thome of the White Sox has 472, Manny Ramirez of the Red Sox has 470, Alex Rodriguez of the Yankees has 464, and a bit distant but not out of the question is Detroit's Gary Sheffield with 455.
600 homers - Sosa's countdown to this milestone resumes at 588 after a one-year layoff. Griffey enters the season with 563, and considering that he hit 35 just two seasons ago, this is by no means out of the question. Junior staying healthy is the question.
300 wins - Could Randy Johnson be a 20-game winner again in his second go-round with the Diamondbacks? Now 43, it might be asking a lot, but if Big Unit were to get there, it could mean two in the same year. Tom Glavine, after receiving the win on Opening Night, is only nine away.
500 saves - There is no history here. Record holder Trevor Hoffman enters this season with 482 saves. 'Nuff said.
755 homers - Part of me hopes that large-necked dude hits the historic homerun... and nobody makes a sound. There's just silence as Bonds limps his Balco body 360 feet. The other side of me, however, will be watching every at-bat, just like I did with McGwire back in '98.